|
|
MoverZ (em-over-zee) is a program for viewing and manipulating biopolymer mass spectra,
capable of performing a wide variety of manual and automated tasks such as peak
labeling, calibration, and automatic data entry into ProFound, Sonar and RADARS.
MoverZ is used with RADARS to view details of the results of automatic peak
labeling and peptide assignment.
MoverZ supports an ever-growing list of mass spectrometer file formats:
Bruker, Perceptive (ms, txt, dat), Finnigan (dta, zta), Applied Biosystems (t2d)
Sciex (sci, qst,wiff), Hitachi (stx), Kratos (run), Micromass Tofspec, M@ldi,
Proteometrics (massml,dcs).
MoverZ contains a high quality peak labeling algorithm that uses signal to noise and
resolution as parameters to determine mono-isotopic peaks. The same parameters
are used in Knexus Automation and RADARS methods so that MoverZ can be used
to determine optimal parameter settings from a small set of data. Subsequently the
parameters can be used in batch processing applications.
MoverZ can display the peaks on an m/z scale or on a mass scale (assuming all ions
are singly charged and protonated). An absolute or relative mass scale can be
chosen. Labels on the peaks can individually be orientated horizontally and
vertically. Peaks can be labeled manually with text or labels can be imported from
PAWS via the clipboard.
Several options for filtering are available: Adaptive Background Correction to remove
sloping base-lines in spectra, Smooth to remove noise and a High Pass Filter to
sharpen peaks.
Part of the spectrum can be displayed with a relative increase or decrease in
intensity to enhance visualization of spectra with part high intensity and part low
intensity peaks.
Graph size can be controlled for reproducible and consistent mass spectra in
reports.
Several mass spectra can be opened at the same time, tiled horizontally and locked
to zoom in and out collectively. Traces can be added to a graph.
Peak lists containing the displayed labels can be exported (including intensity S/N) or
copied to the clipboard (mass or m/z only) for use in other programs.
High quality graphs can be copied to other application for report generation.
Summary:
MoverZ can read most file formats of major mass spectrometer manufacturers. It is integrated with our protein identification tools, Knexus and RADARS. A limited feature version is available for download here. The full version may be purchased separately or included as part of the Knexus or RADARS packages.
MoverZ has a large number of advanced features.
For a full review of its features, please read the tutorial here.
|
